Entity Central Index Key Cover [Abstract] Document Type Document Type Amendment Flag Amendment Flag Document Period End Date Document Period End Date Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Trading Symbol Trading Symbol Entity Registrant Name Entity Registrant Name Entity Central Index Key Current Fiscal Year End Date Current Fiscal Year End Date Entity Filer Category Entity Filer Category Entity Small Business Entity Small Business Entity Emerging Growth Company Entity Emerging Growth Company Entity Extended Transition Period Entity Ex Transition Period Entity Shell Company Entity Shell Company Document Transition Report Document Transition Report Document Quarterly Report Document Quarterly Report Entity Interactive Data Current Entity Interactive Data Current Entity Common Stock, Shares Outstanding Entity Common Stock Shares Outstanding Title of 12(b) Security Security12b Title Security Exchange Name Security Exchange Name Entity Address, Address Line One Entity Address Address Line1 Entity Address, Address Line Two Entity Address Address Line2 Entity Address, City or Town Entity Address City Or Town Entity Address, State or Province Entity Address State Or Province Entity Address, Postal Zip Code Entity Address Postal Zip Code City Area Code City Area Code Local Phone Number Local Phone Number Entity Incorporation, State or Country Code Entity Incorporation State Country Code Entity Current Reporting Status Entity Current Reporting Status Entity Tax Identification Number Entity Tax Identification Number Entity File Number Entity File Number Liabilities Held for Sale Current Liabilities held for sale, non current. Statement Of Financial Position [Abstract] ASSETS Assets [Abstract] Current assets: Assets Current [Abstract] Cash and cash equivalents Cash And Cash Equivalents At Carrying Value Restricted cash - current Restricted Cash Current Royalty receivable Receivables Long Term Contracts Or Programs Prepaid expenses Prepaid Expense Current Other current assets Other Assets Current Total current assets Assets Current Property and equipment, net Property Plant And Equipment Net Operating lease right-of-use asset Operating Lease Right Of Use Asset Other assets Other Assets Noncurrent Total assets Assets LIABILITIES AND STOCKHOLDERS' EQUITY Liabilities And Stockholders Equity [Abstract] Current liabilities: Liabilities Current [Abstract] Accounts payable and other accrued liabilities Accounts Payable And Other Accrued Liabilities Current Accrued compensation Employee Related Liabilities Current Liability related to the sale of future royalties, net - short-term Liabilities Held For Sale Current Current portion of long-term debt Long Term Debt Current Other current liabilities Other Liabilities Current Total current liabilities Liabilities Current Liability related to the sale of future royalties, net - long-term Liabilities Held For Sale Non Current Loan payable - long-term Long Term Loans Payable Operating lease liability Operating Lease Liability Noncurrent Total liabilities Liabilities Stockholders' equity: Stockholders Equity [Abstract] Preferred stock: $0.001 par value; 15,000,000 shares authorized, zero shares issued or outstanding Preferred Stock Value Common stock: $0.001 par value; 500,000,000 shares authorized; 4,449,422 and 4,410,909 shares issued and outstanding at March 31, 2021 and December 31, 2020, respectively Common Stock Value Additional paid-in capital Additional Paid In Capital Common Stock Accumulated deficit Retained Earnings Accumulated Deficit Total stockholders' equity Stockholders Equity Total liabilities and stockholders' equity Liabilities And Stockholders Equity Preferred stock, par value Preferred Stock Par Or Stated Value Per Share Preferred stock, shares authorized Preferred Stock Shares Authorized Preferred stock, shares issued Preferred Stock Shares Issued Preferred stock, shares outstanding Preferred Stock Shares Outstanding Common stock, par value Common Stock Par Or Stated Value Per Share Common stock, shares authorized Common Stock Shares Authorized Common stock, shares issued Common Stock Shares Issued Common stock, shares outstanding Common Stock Shares Outstanding Other expense from continuing operations. Income Statement [Abstract] Royalty revenue Revenue From Contract With Customer Excluding Assessed Tax Revenue from Contract with Customer, Product and Service [Extensible List] Revenue From Contract With Customer Product And Service Extensible List Operating expenses: Operating Expenses [Abstract] Research and development Research And Development Expense General and administrative General And Administrative Expense Loss from operations Operating Income Loss Other expense: Other Nonoperating Income Expense [Abstract] Other expense from continuing operations, net Other Expense From Continuing Operations Loss on extinguishment of debt Gains Losses On Extinguishment Of Debt Net loss from continuing operations Income Loss From Continuing Operations Including Portion Attributable To Noncontrolling Interest Discontinued operations: Income Loss From Discontinued Operations Net Of Tax [Abstract] Income from discontinued operations Income Loss From Discontinued Operations Net Of Tax Net (loss) income Net Income Loss Net loss from continuing operations Income Loss From Continuing Operations Per Basic And Diluted Share Net income from discontinued operations Income Loss From Discontinued Operations Net Of Tax Per Basic And Diluted Share Basic and diluted net (loss) income per basic share Earnings Per Share Basic And Diluted Weighted-average shares used to compute per share calculations Weighted Average Number Of Share Outstanding Basic And Diluted Non-cash interest expense and other. Increase decrease in royalties receivable Increase decrease in operating lease right of use assets. Increase decrease in long term operating lease liability. Increase decrease in assets and liabilities held for sale. Proceeds from sale of future royalties. Transaction costs from sale of future royalties. Statement Of Cash Flows [Abstract] Operating Activities Net Cash Provided By Used In Operating Activities [Abstract] Net (loss) income Profit Loss Adjustments to reconcile net loss to net cash used in operating activities: Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract] Stock-based compensation Share Based Compensation Depreciation and amortization Depreciation Depletion And Amortization Loss on disposal of property and equipment Gain Loss On Disposition Of Assets Gain on sale of Aptevo BioTherapeutics Gain Loss On Sale Of Business Loss on extinguishment of debt Non-cash interest expense and other Non Cash Interest Expense And Other Changes in operating assets and liabilities: Increase Decrease In Operating Capital [Abstract] Royalty receivable Increase Decrease In Royalties Receivable Prepaid expenses and other current assets Increase Decrease In Prepaid Deferred Expense And Other Assets Operating lease right-of-use asset Increase Decrease In Operating Lease Right Of Use Assets Accounts payable, accrued compensation and other liabilities Increase Decrease In Accounts Payable And Accrued Liabilities Long-term operating lease liability Increase Decrease In Long Term Operating Lease Liability Changes in assets and liabilities held for sale Increase Decrease In Assets And Liabilities Held For Sale Net cash used in operating activities Net Cash Provided By Used In Operating Activities Investing Activities Net Cash Provided By Used In Investing Activities [Abstract] Cash received from sale of Aptevo BioTherapeutics Proceeds From Divestiture Of Businesses Purchases of property and equipment Payments To Acquire Property Plant And Equipment Net cash (used in) provided by investing activities Net Cash Provided By Used In Investing Activities Financing Activities Net Cash Provided By Used In Financing Activities [Abstract] Payments of long-term debt, including exit and other fees Repayments Of Long Term Debt Proceeds from sale of future royalties Proceeds From Sale Of Future Royalties Transaction costs from sale of future royalties Transaction Costs From Sale Of Future Royalties Proceeds from exercise of stock options Proceeds From Stock Options Exercised Proceeds from exercise of warrants Proceeds From Warrant Exercises Net cash provided by (used in) financing activities Net Cash Provided By Used In Financing Activities Increase (decrease) in cash, cash equivalents, and restricted cash Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect Cash, cash equivalents, and restricted cash at beginning of period Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations Cash, cash equivalents, and restricted cash at end of period Proceeds from exercise of stock options shares. Proceeds from exercise of stock options value. Proceeds from exercise of warrants share. Proceeds from exercise of warrants value. Cancellation of fractional shares arising from reverse stock split. Statement Of Stockholders Equity [Abstract] Statement [Table] Statement [Table] Equity Components Statement Equity Components [Axis] Equity Component Equity Component [Domain] Common Stock Common Stock [Member] Additional Paid-In Capital Additional Paid In Capital [Member] Accumulated Deficit Retained Earnings [Member] Statement [Line Items] Statement [Line Items] Balance Balance (in shares) Shares Outstanding Proceeds from exercise of stock options Proceeds From Exercise Of Stock Options Value Proceeds from exercise of stock options (in shares) Proceeds From Exercise Of Stock Options Shares Proceeds from exercise of warrants Proceeds From Exercise Of Warrants Value Proceeds from exercise of warrants (in shares) Proceeds From Exercise Of Warrants Share Cancellation of fractional shares arising from reverse stock split Cancellation Of Fractional Shares Arising From Reverse Stock Split Stock-based compensation Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value Net income (loss) for the period Balance Balance (in shares) Accounting Policies [Abstract] Nature of Business and Significant Accounting Policies Organization Consolidation Basis Of Presentation Business Description And Accounting Policies [Text Block] Discontinued Operations And Disposal Groups [Abstract] Discontinued Operations Disposal Groups Including Discontinued Operations Disclosure [Text Block] Organization Consolidation And Presentation Of Financial Statements [Abstract] Collaboration Agreements Collaborative Arrangement Disclosure [Text Block] Fair Value Disclosures [Abstract] Fair Value Measurements Fair Value Disclosures [Text Block] Cash And Cash Equivalents [Abstract] Cash, Cash Equivalents, and Restricted Cash Cash And Cash Equivalents Disclosure [Text Block] Debt Disclosure [Abstract] Debt Debt Disclosure [Text Block] Liability related to sale of future royalties disclosure. Sale of future royalties liability disclosure abstract Sale Of Future Royalties Liability Disclosure [Abstract] Liability Related to Sale of Future Royalties Liability Related To Sale Of Future Royalties Disclosure [Text Block] Leases [Abstract] Leases Leases Of Lessee Disclosure [Text Block] Earnings Per Share [Abstract] Net Income (Loss) per Share Earnings Per Share [Text Block] Equity [Abstract] Equity Shareholders Equity And Share Based Payments [Text Block] Basis of Presentation Basis Of Presentation And Significant Accounting Policies [Text Block] Use of Estimates Use Of Estimates Liability related to sale of future royalties and non-cash interest expense. Liability Related to Sale of Future Royalties and Non-Cash Interest Expense Liability Related To Sale Of Future Royalties And Non Cash Interest Expense Policy [Text Block] Debt Modification Debt Policy [Text Block] Other significant accounting policy. Other Significant Accounting Policies Other Significant Accounting Policy [Text Block] Recent accounting pronouncements not yet adopted. Recent Accounting Pronouncements Not Yet Adopted Recent Accounting Pronouncements Not Yet Adopted Policy [Text Block] Summary of Reconciliation of Carrying Amounts of Assets and Liabilities and Income (Loss) from Discontinued Operation Schedule Of Disposal Groups Including Discontinued Operations Income Statement Balance Sheet And Additional Disclosures [Text Block] Schedule of Cash, Cash Equivalents and Current Restricted Cash Schedule Of Cash And Cash Equivalents Table [Text Block] Schedule of changes in the liability related to the sale of future royalties. Schedule of Changes in the Liability Related to the Sale of Future Royalties Schedule Of Changes In Liability Related To Sale Of Future Royalties Table [Text Block] Components of Lease Expense Lease Cost Table [Text Block] Summary of right of use assets acquired under operating leases. Summary of Right of Use Assets Acquired Under Operating Leases Summary Of Right Of Use Assets Acquired Under Operating Leases Table [Text Block] Computation of Basic and Diluted Net Loss per Share Schedule Of Earnings Per Share Basic And Diluted Table [Text Block] Summary of Potentially Dilutive Shares Excluded from Calculation of Net Loss Per Share Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block] Summary of Stock-based Compensation Expense Includes Amortization of Stock Options and Restricted Stock Units Granted Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Text Block] Assumptions used in Valuing the Stock Options Granted under Black-Scholes Valuation Model Schedule Of Share Based Payment Award Stock Options Valuation Assumptions Table [Text Block] Summary of Stock Option Activity Schedule Of Share Based Compensation Stock Options Activity Table [Text Block] Summary of RSU Activity Schedule Of Share Based Compensation Restricted Stock Units Award Activity Table [Text Block] Debt Instrument [Table] Debt Instrument [Table] Counterparty Name Counterparty Name [Axis] Counterparty Name Repurchase Agreement Counterparty Name [Domain] RUXIENCE R U X I E N C E R U X I E N C E [Member] Statistical Measurement Range [Axis] Statistical Measurement Range [Member] Maximum Maximum [Member] Minimum [Member] Minimum [Member] Legal Entity Legal Entity [Axis] Entity Entity [Domain] Mid Cap financial [Member] Mid Cap Financial Mid Cap Financial [Member] H C R H C R [Member] Debt Instrument [Line Items] Debt Instrument [Line Items] Accumulated deficit Net cash used in operating activities Fractional shares reverse stock split. Reverse stock split description Stockholders Equity Reverse Stock Split Stock split, conversion ratio Stockholders Equity Note Stock Split Conversion Ratio1 Fractional shares reverse stock split Fractional Shares Reverse Stock Split Proceeds from Sale of Investments. Payment of Royalty Purchase Agreement, Percentage. Payment of royalty interest, percentage. Proceeds from Sale of Investments Proceeds From Sale Of Investments Revenue from related Parties Revenue From Related Parties Payment of royalty purchase agreement Payment Of Royalty Purchase Agreement Percentage Payment of royalty interest Payment Of Royalty Interest Percentage Proceeds from sale of investments used. Payment of amount outstanding. Proceeds from sale of investments used Proceeds From Sale Of Investments Used Payment Of Amount Outstanding Payment Of Amount Outstanding Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Table] Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Table] Disposal Group Classification Disposal Group Classification [Axis] Disposal Group Classification Disposal Group Classification [Domain] Hyperimmune business. Hyperimmune Business Hyperimmune Business [Member] Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items] Income Statement Balance Sheet And Additional Disclosures By Disposal Groups Including Discontinued Operations [Line Items] Net gain on sale of business Disposal group including discontinued operations deferred revenue. Milestone payments. Loss from operations - Aptevo BioTherapeutics Discontinued Operation Gain Loss On Disposal Of Discontinued Operation Net Of Tax Gain on sale of Aptevo BioTherapeutics Disposal Group Not Discontinued Operation Gain Loss On Disposal Estimated deferred payment from Medexus Disposal Group Including Discontinued Operations Deferred Revenue Milestone payment Milestone Payment Depreciation or capital expenditures. Investing non-cash items Other non-cash operating activities discontinued operations. Gain in discontinued operations, net of tax Amortization Adjustment For Amortization Depreciation or capital expenditure Depreciation Or Capital Expenditures Investing non-cash items Investing Non Cash Items Estimated Deferred Payment From Medexus Other Noncash Operating Activities Discontinued Operations Reduction in research and development expense. Reduction in research and development expense Reduction In Research And Development Expense Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value Hierarchy and NAV Fair Value By Fair Value Hierarchy Level [Axis] Fair Value Hierarchy and NAV Fair Value Measurements Fair Value Hierarchy [Domain] Level Two Fair Value Inputs Level2 [Member] Level Three Fair Value Inputs Level3 [Member] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Money market funds Money Market Funds At Carrying Value Fair value assets Assets Fair Value Disclosure Cash equivalents maturity period. Schedule Of Restricted Cash And Cash Equivalents [Table] Schedule Of Restricted Cash And Cash Equivalents [Table] Credit Facility Credit Facility [Axis] Credit Facility Credit Facility [Domain] Letter of Credit Letter Of Credit [Member] Restricted Cash And Cash Equivalents Items [Line Items] Restricted Cash And Cash Equivalents Items [Line Items] Cash equivalents, maturity period Cash Equivalents Maturity Period Current restricted cash Cash Cash Cash equivalents Cash Equivalents At Carrying Value Total cash, cash equivalents, and restricted cash Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Line Of Credit Facility [Table] Line Of Credit Facility [Table] Debt Instrument Debt Instrument [Axis] Debt Instrument, Name Debt Instrument Name [Domain] Credit agreement member. Credit Agreement [Member] Credit Agreement [Member] Variable Rate Variable Rate [Axis] Variable Rate Variable Rate [Domain] London Interbank Offered Rate LIBOR [Member] London Interbank Offered Rate L I B O R [Member] Business Acquisition Business Acquisition [Axis] Business Acquisition, Acquiree Business Acquisition Acquiree [Domain] Tang [member]. Tang Tang [Member] Scenario Statement Scenario [Axis] Scenario Scenario Unspecified [Domain] Scenario Forecast Scenario Forecast [Member] Line Of Credit Facility [Line Items] Line Of Credit Facility [Line Items] Maximum borrowing capacity Line Of Credit Facility Maximum Borrowing Capacity Line of credit facility, used borrowing capacity Line Of Credit Facility Current Borrowing Capacity Line of credit facility, borrowing capacity, description Line Of Credit Facility Borrowing Capacity Description Interest rate Derivative Fixed Interest Rate Floor interest rate Derivative Floor Interest Rate Cap interest rate Derivative Cap Interest Rate Percentage of common stock shares issued and outstanding. Purchase of shares of common stock Stock Issued During Period Shares Acquisitions Percentage of common stock shares issued and outstanding Percentage Of Common Stock Shares Issued And Outstanding Business acquisition, description Business Acquisition Description Of Acquired Entity Principal balance payable date Principal balance payable date Principal Balance Payable Date Repayments of subordinated debt Amendment in lieu of the formula-based fee Amendment Fees Remaining principal balance payable Remaining Principal Balance Payable Remaining Principal Balance Payable Liability Class Fair Value By Liability Class [Axis] Fair Value by Liability Class Fair Value Liabilities Measured On Recurring Basis Unobservable Input Reconciliation By Liability Class [Domain] Liability Liability [Member] Non cash interest expense. Proceeds from royalties received Proceeds From Royalties Received Transaction costs Deferred Finance Costs Gross Non-cash interest expense Non Cash Interest Expense Interest rate, effective percentage Debt Instrument Interest Rate Effective Percentage Liability related to sale of future royalties. Liability related to sale of future royalties current. Liability related to sale of future royalties non current. Liability related to sale of future royalties, beginning balance Liability Related To Sale Of Future Royalties Deferred transaction costs Deferred Costs Current And Noncurrent Liability related to sale of future royalties, ending balance Current portion of liability related to sale of future royalties Liability Related To Sale Of Future Royalties Current Liability related to sale of future royalties, non-current Liability Related To Sale Of Future Royalties Non Current Initial operating lease term date. Number of operating lease renewal options. Operating lease termination option written notice period. Lessee operating lease unamortized tenant improvement allowance interest rate. Lessee operating lease unamortized real estate taxes interest rate. Lessee Lease Description [Table] Lessee Lease Description [Table] Long-Lived Tangible Asset Property Plant And Equipment By Type [Axis] Long-Lived Tangible Asset Property Plant And Equipment Type [Domain] Office space lease. Office Space Lease Office Space Lease [Member] Collaborative Arrangement and Arrangement Other than Collaborative Type Of Arrangement [Axis] Collaborative Arrangement and Arrangement Other than Collaborative Arrangements And Nonarrangement Transactions [Member] Two lease renewal option. Renewal Option Two Two Lease Renewal Option [Member] Lessee Lease Description [Line Items] Lessee Lease Description [Line Items] Initial operating lease term date Initial Operating Lease Term Date Operating lease renewal option description Lessee Operating Lease Option To Extend Operating lease renewal option term Lessee Operating Lease Renewal Term Number of operating lease renewal option Number Of Operating Lease Renewal Options Operating lease option to extend Lessee Operating Lease Existence Of Option To Extend Operating lease termination option written notice period Operating Lease Termination Option Written Notice Period Operating lease termination option unamortized tenant improvement allowance interest rate Lessee Operating Lease Unamortized Tenant Improvement Allowance Interest Rate Operating lease termination option unamortized real estate taxes interest rate Lessee Operating Lease Unamortized Real Estate Taxes Interest Rate Variable expense Variable Lease Cost Operating lease property number of units. Operating lease property number of copiers. Operating lease number of piece for lab equipment Operating Lease Property Number Of Lab Equipment Operating lease number of copiers Operating Lease Property Number Of Copiers Finance lease number of equipment. Financing lease number of equipment Finance Lease Number Of Equipment Financing lease payments Finance Lease Principal Payments Operating lease cost Operating Lease Cost Finance lease cost: Lease Cost [Abstract] Amortization of right-of-use assets Finance Lease Right Of Use Asset Amortization Interest on lease liabilities Finance Lease Interest Expense Total lease cost Lease Cost Operating leases, excluding Seattle office lease. Operating Leases, Excluding Seattle Office Lease Operating Leases Excluding Seattle Office Lease [Member] Seattle office lease including amendment. Seattle Office Lease, Including Amendment Seattle Office Lease Including Amendment [Member] Total operating leases Right Of Use Asset Obtained In Exchange For Operating Lease Liability For operating leases Operating Lease Payments Long term portion of operating lease liabilities Weighted average remaining lease term for operating leases Operating Lease Weighted Average Remaining Lease Term1 Weighted discount rate for operating leases Operating Lease Weighted Average Discount Rate Percent Net loss from continuing operations Income from discontinued operations Discontinued Operation Income Loss From Discontinued Operation Before Income Tax Basic and diluted net income (loss) per share: Earnings Per Share Basic And Diluted [Abstract] Schedule of earnings per share basic and diluted. Schedule of earnings per share basic and diluted. Schedule Of Earnings Per Share Basic And Diluted [Table] Schedule Of Earnings Per Share Basic And Diluted [Table] Antidilutive Securities Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis] Antidilutive Securities, Name Antidilutive Securities Name [Domain] Warrants Warrant [Member] Outstanding Options to Purchase Common Stock Employee Stock Option [Member] Unvested RSUs Restricted Stock Units R S U [Member] Schedule Of Earnings Per Share Basic And Diluted [Line Items] Schedule Of Earnings Per Share Basic And Diluted [Line Items] Anti-dilutive shares excluded from calculation of diluted net loss per share Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount Aggregate offering price. Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Equity distribution agreement. Equity Distribution Agreement Equity Distribution Agreement [Member] Purchase Agreement Purchase Agreement [Member] Related Party Transaction Related Party Transaction [Axis] Related Party Transaction Related Party Transaction [Domain] Broadridge Corporate Issuer Solutions. Broadridge Corporate Issuer Solutions Broadridge Corporate Issuer Solutions [Member] Class of Stock Statement Class Of Stock [Axis] Class of Stock Class Of Stock [Domain] Series A Junior Participating Preferred Stock. Series A Junior Participating Preferred Stock [Member] Series A Junior Participating Preferred Stock [Member] Plan Name Plan Name [Axis] Plan Name Plan Name [Domain] Converted equity awards incentive plan. Converted Equity Awards Incentive Plan Converted Equity Awards Incentive Plan [Member] Two thousand sixteen stock incentive plan. 2016 Stock Incentive Plan Two Thousand Sixteen Stock Incentive Plan [Member] Title of Individual Title Of Individual [Axis] Title of Individual Title Of Individual With Relationship To Entity [Domain] Non-employee directors. Non-employee Directors Non Employee Directors [Member] Award Type Award Type [Axis] Award Type Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain] Unvested RSUs Two thousand eighteen stock incentive plan. 2018 Stock Incentive Plan Two Thousand Eighteen Stock Incentive Plan [Member] Stock Option Vesting Vesting [Axis] Vesting Vesting [Domain] Tranche One Share Based Compensation Award Tranche One [Member] Tranche Two Share Based Compensation Award Tranche Two [Member] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Aggregate offering price Aggregate Offering Price Issuance of common stock shares Stock Issued During Period Shares New Issues Commitment to purchase shares of common stock maximum amount. Issuance of common stock, net Stock Issued During Period Value New Issues Commitment to purchase shares of common stock, maximum amount Commitment To Purchase Shares Of Common Stock Maximum Amount Minimum prevailing market price to direct purchase Share Price Dividend declared of preferred share purchase right. Share portion entitled to purchase by rights. Percentage Of Beneficial Ownership. Preferred share purchase right Dividend Declared Of Preferred Share Purchase Right Share portion entitled to purchase by rights. Share Portion Entitled To Purchase By Rights1 Preferred stock exercise price Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1 Percentage of beneficial ownership Percentage Of Beneficial Ownership Stock authorized for issuance under Stock Plan Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Authorized Stock plan vesting period Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Period1 Stock plan termination period Sharebased Compensation Arrangement By Sharebased Payment Award Expiration Period Increase in number of authorized shares issuable. Increase of authorized shares issuable Increase In Number Of Authorized Shares Issuable Share based compensation arrangement by share based payment award maximum number of returning shares from old plan to be added to shares reserve. Maximum number of returning shares from old plan to be add to shares reserve Share Based Compensation Arrangement By Share Based Payment Award Maximum Number Of Returning Shares From Old Plan To Be Added To Shares Reserve Number of shares available for grant Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Income Statement Location Income Statement Location [Axis] Income Statement Location Income Statement Location [Domain] Research and Development Research And Development Expense [Member] General and Administrative General And Administrative Expense [Member] Stock-based compensation expense Allocated Share Based Compensation Expense Expected dividend yield Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate Expected volatility Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Risk-free interest rate Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Expected average life of options Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1 Share based compensation arrangement by share based payment award forfeiture rate. Share based compensation arrangement by share based payment award fair value assumptions expected volatility share price. Estimated forfeiture rate Share Based Compensation Arrangement By Share Based Payment Award Forfeiture Rate Expected volatility Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Share Price Number of Shares, Outstanding, Beginning balance Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number Number of Shares, Granted Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross Number of Shares, Exercised Stock Issued During Period Shares Stock Options Exercised Number of Shares, Forfeited Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period Number of Shares, Outstanding, Ending balance Number of Shares, Exercisable Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number Weighted-Average Exercise Price, Outstanding, Beginning balance Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price Weighted-Average Exercise Price, Granted Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price Weighted-Average Exercise Price, Exercised Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price Weighted-Average Exercise Price, Forfeited Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price Weighted-Average Exercise Price, Outstanding, Ending balance Weighted-Average Exercise Price, Exercisable Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price Weighted-Average Remaining Term, Outstanding Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2 Weighted-Average Remaining Term, Exercisable Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1 Share based compensation arrangement by share based payment award options granted intrinsic value. Share based compensation arrangement by share based payment award options forfeitures in period intrinsic value. Aggregate Intrinsic Value, Outstanding, Beginning balance Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value Aggregate Intrinsic Value, Granted Share Based Compensation Arrangement By Share Based Payment Award Options Granted Intrinsic Value Aggregate Intrinsic Value, Exercised Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value Aggregate Intrinsic Value, Forfeited Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period Intrinsic Value Aggregate Intrinsic Value, Outstanding, Ending balance Aggregate Intrinsic Value, Exercisable Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1 Sharebased compensation arrangement by sharebased payment award options expected to vest weighted average period. Share based compensation arrangement by share based payment award options outstanding and exercisable weighted average remaining contractual term. Unrecognized compensation expense Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Stock Options Options expected to vest, weighted average period Sharebased Compensation Arrangement By Sharebased Payment Award Options Expected To Vest Weighted Average Period Options outstanding and exercisable weighted average remaining contractual life Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding And Exercisable Weighted Average Remaining Contractual Term Share based compensation arrangement by share based payment award equity instrument other than options expected to vest number. Number of Units, Outstanding, Beginning balance Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number Number of Units, Granted Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Number of Units, Outstanding, Ending balance Number of Units, Expected to Vest Share Based Compensation Arrangement By Share Based Payment Award Equity Instrument Other Than Options Expected To Vest Number Share based compensation arrangement by share based payment award equity instruments other than options, expected to vest, weighted average grant date fair value. Weighted Average Fair Value per Unit, Outstanding Beginning Balance Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value Weighted Average Fair Value per Unit, Granted Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value Weighted Average Fair Value per Unit, Outstanding Ending Balance Weighted Average Fair Value per Unit, Expected to Vest Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Expected To Vest Weighted Average Grant Date Fair Value Share based compensation arrangement by share based payment award equity instruments other than options aggregate fair value. Share based compensation arrangement by share based payment award equity instruments other than options aggregate fair value granted. Share based compensation arrangement by share based payment award equity instruments other than options aggregate fair value expect to vest. Aggregate Fair Value, Outstanding, Beginning balance Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Aggregate Fair Value Aggregate Fair Value, Granted Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Aggregate Fair Value Granted Aggregate Fair Value, Outstanding, Ending balance Aggregate Fair Value, Expected to Vest Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Aggregate Fair Value Expect To Vest Unrecognized compensation expense Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Share Based Awards Other Than Options Number of warrants issued. Number of common stock shares to be issued exercise of prefunded warrants. Pre funded warrants exercise price. Pre funded warrants and rights outstanding term. Prefunded warrant expiration date. Number of common stock to be issued up conversion of warrants Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights Number of warrants issued Number Of Warrants Issued Warrants outstanding, term Warrants And Rights Outstanding Term Number of common stock to be issued exercise of prefunded warrants Number Of Common Stock Shares To Be Issued Exercise Of Prefunded Warrants Pre funded warrants exercise price, per share Pre Funded Warrants Exercise Price Pre funded warrants outstanding, term Pre Funded Warrants And Rights Outstanding Term Pre funded warrants expire date Prefunded Warrant Expiration Date Warrants outstanding Class Of Warrant Or Right Outstanding