A.G.P. / Alliance Global Partners

590 Madison Ave., 28th Floor

New York, NY 10022

July 14, 2023

VIA EDGAR

U.S. Securities and Exchange Commission

Division of Corporation Finance

Office of Life Sciences

100 F Street, N.E.

Washington, D.C. 20549

	Re:	Aptevo Therapeutics Inc.
		Registration Statement on Form S-1
		File No. 333-273067

Ladies and Gentlemen:

Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended (the “Securities Act”), A.G.P / Alliance Global Partners, as representative of the underwriters, hereby requests acceleration of the effective date of the above-referenced Registration Statement so that it will become effective at 5:30pm Eastern Time on July 18, 2023 or as soon thereafter as practicable.

	Very truly yours,
	A.G.P / Alliance Global Partners
	By:	/s/ Thomas J. Higgins
	Name:	Thomas J. Higgins
	Title:	Managing Director

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