Aptevo Therapeutics Announces Inclusion in the Russell Microcap(R) Index
Membership in the Russell Microcap®
"We are pleased to be joining the Russell Microcap®
An immuno-oncology company, Aptevo is focused on discovering and developing novel therapeutics for difficult-to-treat hematologic malignances and solid tumors. Drug candidates are developed from the Company's proprietary platforms, ADAPTIR and ADAPTIR-FLEX, which are capable of generating highly differentiated bispecific and multi-specific antibodies. The Company recently announced completion of the dose escalation part of a Phase 1b clinical trial with lead drug candidate APVO436 for the treatment of acute myeloid leukemia (AML) and myelodysplastic syndrome. Interim results showed the drug was well tolerated and had a manageable side effect profile. The primary endpoint - identification of a recommended Phase 2 dose - was also achieved. The Company also announced activation of the expansion part of the trial, which will simultaneously evaluate APVO436 in five cohorts of 18 patients each (N=90) in both combination and monotherapy.
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Safe Harbor Statement
This press release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements, other than statements of historical fact, including, without limitation, Aptevo's expectations about the activity, efficacy and safety of its therapeutic candidates and potential use of any such candidates as therapeutics for treatment of disease, advancement of its clinical trials and its expectations regarding the effectiveness of its ADAPTIR and ADAPTIR-FLEX platforms, and any other statements containing the words "may," "believes," "expects," "anticipates," "hopes," "intends," "optimism," "potential," "designed," "engineered," "breakthrough," "innovative," "innovation," "promising," "plans," "forecasts," "estimates," "will" and similar expressions are intended to identify forward-looking statements. These forward-looking statements are based on Aptevo's current intentions, beliefs and expectations regarding future events. Aptevo cannot guarantee that any forward-looking statement will be accurate. Investors should realize that if underlying assumptions prove inaccurate or unknown risks or uncertainties materialize, actual results could differ materially from Aptevo's expectations. Investors are, therefore, cautioned not to place undue reliance on any forward-looking statement.
There are a number of important factors that could cause Aptevo's actual results to differ materially from those indicated by such forward-looking statements, including a deterioration in Aptevo's business or prospects; adverse developments in clinical development, including unexpected safety issues observed during a clinical trial; adverse developments in the